Tag Archives: Healthy Aging

Secret to a Long and Happy Life

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On CNBC’s Make It, 107-year-old Shirley Hodes shares her secret to a long and happy life: Don’t wait for your dreams to come true.

Shirley Hodes, who celebrated her 107th birthday earlier this month in North Carolina, says, “Not everyone has their dreams come true.” If you want to be happy in life, especially as you age, “you must look at other things besides dreams.”

That philosophy means reorienting yourself towards finding joy in small things, in what you can control, and in wanting what you already have. It is about being grateful.

“You must be content with who you are and what you can expect of yourself. Find things that are satisfying,” Hodes says.

Cultivating this kind of happiness mindset requires effort. But the work can pay off: Positivity is linked to a longer and healthier life.

Here are top tips for staying happy as you get older.

  • Think of yourself as fortunate and blessed. Be thankful for all the things and people currently in your life.
  • Believe that tomorrow will be better than today.
  • Focus less on what others have and more on the aspects of life you can feel grateful for.  Don’t get swept up in jealousy or resentment,
  • Find delight daily in the small things. I listened to books on tape, took walks, watched old movies on TV, and had a scoop of ice cream after dinner. Most importantly, family and friends.

Source: 107-year-old shares her secret to a long and happy life: Don’t wait for your dreams to come true  https://www.cnbc.com/2023/09/21/107-year-old-shares-her-secrets-to-happiness-as-you-age.html

Vitamin K2

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Healthy levels of vitamin K2 support your heart, blood circulation, and bones.

Vitamin K2 is getting a lot of attention for its many health benefits. Vitamin K2 plays a role in regulating your blood pressure. It helps keep your bones strong. And it contributes to minimizing your risk of heart disease.

Vitamin K2 is also a powerful nutrient that is essential to many aspects of your health.  It is a fat-soluble vitamin that must be consumed in dietary or supplement form since our bodies can’t produce sufficient amounts on their own. Maintaining healthy levels of vitamin K2 supports your heart, blood circulation, and bones. Some think vitamin K2 may be the missing link between diet and several chronic diseases.

Vitamin K2 (MK-7)

Vitamin K2 can be divided into several different subtypes. The most important ones are MK-4 and MK-7. Research has shown that the long-chain form of vitamin K2 called menaquinone-7 (MK-7) offers more advanced benefits than its short-chain form, menaquinone-4 (MK-4).

Unlike MK-4, MK-7 allows for smaller, more convenient doses because it accumulates in the bloodstream. MK-7 beats out MK-4 with better accumulation and absorption rates in the bloodstream. MK-7 also aids in bone mineral density, helping with bone quality and strength – making it the superior form of K2.

Vitamins K2 and D3 are powerful for teeth and bone health. D3 helps your body metabolize calcium by directing it to your teeth and bones, but this job isn’t complete without K2. Vitamin K2 activates the proteins needed to deposit calcium in the correct spots.

Combat Common Deficiencies

In a survey from the National Health and Nutrition Examination, 25% of Americans were found to be at risk of a vitamin D deficiency. In comparison, 8% were vitamin D deficient – an increase from the previous 20 years. This research shows how widespread low vitamin D levels can be, and when left untreated, vitamin D deficiency can impact bone health, mood, and energy levels.

Healthy Blood Flow

Some of the calcium we consume can end up being stored in blood vessels and soft tissues, constricting blood flow to your heart. Vitamin K2 draws this excess calcium away from the soft tissue, aiding blood circulation.

Chronic Diseases Greatest Threat to Life Expectancy

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Chronic diseases are the greatest threat to life expectancy and public health, killing far more Americans between 35 and 64 every year.  ~ Washington Post

While opioids and gun violence in the U.S. have rightly seized the media and public’s attention, heart disease and cancer remained, even at the height of the COVID-19 pandemic, the leading causes of death for people 35 to 64, according to a Washington Post analysis of mortality data.

And many other conditions  have become more common, including diabetes and liver disease. These chronic ailments are the primary reason American life expectancy has been poor compared with other Westen nations.

The pandemic amplified a racial gap in life expectancy that had been narrowing in recent decades. In 2021, life expectancy for Native Americans was 65 years; for Black Americans, 71; for White Americans, 76; for Hispanic Americans, 78; and for Asian Americans 84.

Life expectancy is a wide-angle snapshot of average death rates for people in different places or age groups. The life expectancy metric is a reasonably good measure of a nation’s overall health. And America’s is not very good.

In essence, the U.S. healthcare system geared toward disease and illness treatment rather than prevention. Health care is “the only business that doesn’t reward for quality care. All we reward for is volume. Do more, and you’re going to get more money,” Michael Imburgia, a Louisville cardiologist said.

The rate of obesity deaths for adults 35 to 64 doubled from 1979 to 2000, then doubled again from 2000 to 2019. In 2005, a special reportin the New England Journal of Medicine warned that the rise of obesity would eventually halt and reverse historical trends in life expectancy. That warning generated little reaction.

Obesity is one reason progress against heart disease, after accelerating between 1980 and 2000, has slowed, experts say. Obesity is poised to overtake tobacco as the No. 1 preventable cause of cancer, according to Otis Brawley, an oncologist and epidemiologist at Johns Hopkins University.

References:

  1. https://www.washingtonpost.com/health/interactive/2023/american-life-expectancy-dropping/

Nitric Oxide Sources

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Nitric oxide is a molecule that is very important to the way the body works, including how the blood flows, how the immune system works, and how the brain works.

Adding nitric oxide to your diet may help your health in a number of ways, such as lowering your blood pressure, improving your blood flow and exercise performance, and reducing inflammation.

Foods that are naturally high in nitric oxide or help the body produce more nitric oxide include:

  • Beets: Beets are a rich source of nitrates, which the body converts into nitric oxide. They also contain antioxidants and other nutrients that can support overall health.
  • Spinach: Spinach is another excellent source of nitrates and contains various other nutrients, including vitamins and minerals.
  • Berries: Many berries, including blueberries, raspberries, and blackberries, contain antioxidants and other compounds that may support nitric oxide production.
  • Pomegranate: Pomegranate is high in antioxidants and has been shown to support nitric oxide production in the body.

Nitric Oxide

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Many people think that taking nitric oxide supplements will enhance blood flow in the body to improve performance in sports, promote healing, enhance heart health, and provide many other potential benefits.

To reduce inflammation or improve your digestion, sleep quality, immunity, memory, and behavior, you need to know about nitric oxide.

Nitric oxide is an essential molecule required for overall health. As a vasodilator, nitric oxide signals the blood vessels to relax, allowing them to expand.

Nitric oxide is most known for its role in heart health as it is a potent vasodilator and regulator of blood pressure, making your blood vessels supple and flexible, which allows them to withstand pressure changes.

What is Nitric Oxide?

Nitric oxide is a gaseous molecule synthesized from the amino acid L-arginine with molecular oxygen by synthases, neuronal (nNOS), endothelial (eNOS), and inducible (iNOS).

Nitric oxide performs crucial roles in vascular and neuronal signal transduction, smooth muscle contractility, bioenergetics, platelet adhesion and aggregation, immunity, and cell death regulation.

Benefits of Nitric Oxide:

Research shows that Nitric oxide has blood-flow-enhancing effects and supports healthy delivery of oxygen and nutrients to the muscles during exercise.

There may be benefits of Nitric oxide supplements for sexual enhancement and erectile dysfunction. Studies imply that some men can use Nitric oxide as a natural way to aid with erectile issues and maintain a healthy sexual experience.

Nitric oxide is produced by the endothelial cells lining the arteries; however, Nitric Oxide levels can naturally decrease as you age.

As you age, your body slows down and produces less of almost everything than it did in your younger years.

Additionally, many unknowingly use antibacterial mouthwash or acid blockers to cut down the acid in their stomach. Both of these products destroy the good bacteria in your mouth and your gut. You need these bacteria to convert certain nutrients in your body into Nitric Oxide.

Regular physical exercise is a great way to enable and empower our body’s function. It helps distribute much-needed life-giving oxygen and healthy nutrients to the rest of the body. However, exercising 24/7 isn’t reasonably achievable for the everyday person.

You can boost naturally Nitric oxide levels in your body. A diet of foods such as spinach, beets, celery, arugula lettuce, iceberg lettuce, carrots, parsley, cabbage, radishes, collard greens, etc., have small amounts of nitric oxide. Changes in diet can improve Nitric oxide levels.

VO2 Max

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VO2 max is the single best indicator of cardiorespiratory fitness.

When it comes to measuring fitness and longevity, there is one number cardiovascular experts believe rule them all: VO2 max. VO2 max — or your oxygen uptake — shows how much oxygen your body absorbs and uses while working out. V is for volume, O2 is for oxygen and max is for maximum. Many health experts consider it the single best indicator of cardiorespiratory fitness, and research has found it correlates to longevity as well.

A person’s maximal oxygen consumption, also known as VO2 max—a measurement of how well the body takes in and uses oxygen while exercising at a high intensity—is a useful statistic to gauge fitness and cardiovascular health. A higher VO2 max score means the heart and lungs are transporting more oxygen-rich blood to the muscles, increasing energy production and maximizing athletic performance.

The most accurate VO2 max tests are done in a laboratory where you are hooked up to a mask that measures oxygen consumption as you exercise. VO2 max is measured in milliliters of oxygen a minute per kilogram of body weight. The more oxygen you burn, the fitter you are.

Activity level Average VO2 max
Sedentary 27-30 mL/kg/min
Active 33.0-36.9 mL/kg/min
Very active ≤ 77 mL/kg/min

Source:  Cleveland Clinic.

If you are on a treadmill, you are told to walk or run faster and faster until your oxygen consumption stops rising. If you go beyond this point, you will increasingly be using anaerobic energy—which doesn’t burn oxygen—and you will have trouble sustaining it for long periods.

References:

  1. https://health.clevelandclinic.org/what-is-vo2-max-and-how-to-calculate-it/
  2. https://www.barrons.com/articles/vo2-max-test-increase-fitness-age-128c53cd

Apple cider vinegar can lower blood sugar

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Registered dietitian Carol Johnston, a professor of nutrition and an associate dean in the College of Health Solutions at Arizona State University, has been studying the effects of acetic acid, the main component of vinegar, on diabetic blood glucose levels, since 2004.

“If I was to show that vinegar slows progression to diabetes, then I would need hundreds of people and millions of dollars to do the studies, because diabetes has a lot of causes, including genetics,” Johnston said.

But studies do show acetic acid can be used as one tool in helping people lower blood sugar. A 2019 randomized clinical trial found “a 10 point decrease in fasting glucose concentrations,” Johnston said. “They used two ‘spoons’ of vinegar in a glass of water twice a day.”

In Johnston’s research, the people who benefited most from the use of vinegar were insulin-resistant, a condition called prediabetes. “In those with prediabetes, it was too good to be true,” she said. “It fell a good bit and stayed that way. It may be this is the group that could benefit the most.”

It’s not just apple cider – the antiglycemic response can be induced by any sort of vinegar: red and white wine vinegars, pomegranate vinegar or even white distilled vinegar.

“Basically, what acetic acid is doing is blocking the absorption of starch,” Johnston said. “If my study subjects eat a starch and add vinegar, blood glucose will go down. But if they drink sugar water and add vinegar, nothing happens. So if you’re having bacon and eggs, don’t bother. It only helps if you are consuming a starch.”

“If you’re taking a diabetes drug, the vinegar could amplify the effects of your meds,” she warned, “and your doctor might want to adjust your dosage.” Studies show the vinegar can reduce blood pressure, triglycerides and total cholesterol in rodents fed a high-fat, cholesterol-rich diet. But full-blown studies have not been conducted in humans.

Freeman, who serves on the American College of Cardiology’s prevention board, said there could be some benefit because of its antioxidant properties, like other heart-healthy fruits and vegetables, such as broccoli and blueberries.

Lifestyle Changes to Diet, Sleep, and Exercise—Paired with interventions Like Relaxation Exercises Could Reverse the Aging Process

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A group of mature women lowered their biological age by an average of 5 years in just 8 weeks by lifestyle change consisting of exercise, healthy diet and adequate sleep. 

In the United States, dix in ten adults have at least one chronic disease and four in ten adults have two or more [1]. These diseases are a major cause of morbidity and mortality and they put a significant burden on the U.S. healthcare system as well as the society at large [2].

Aging has been identified as a common driver of chronic diseases and an important target for extending Americans’ healthspan [3]. Life expectancy for Americans has increased dramatically, although not all of the years gained are healthy. It has been estimated that if we improve Americans’ collective healthspan by just one year the calculated savings are worth $38 trillion dollars, and if by 10 years those savings jump to $367 trillion dollars [4].

Biological age clocks, based on DNA methylation marks, have become important surrogate markers to assess the effectiveness of interventions at reducing biological age, with the expectation that biological age reductions will compress morbidity and extend mortality [5, 6].

Lifestyle changes to diet, sleep, and exercise—paired with interventions like relaxation exercises and supplements—could reverse the aging process, according to new research.

Six women between the ages of 46 and 65 underwent an eight-week program that included alterations to diet, sleep, and exercise. They were also given relaxation guidance, probiotic and phytonutrient supplements, and nutritional coaching.

Blood tests showed a reduction in biological age of up to 11 years in five of the six women, with the average participant experiencing a 4.6-year decrease, according to the study, published in March in the journal Aging.

References:

  1. About chronic disease. Center for Disease Control. 2022. https://www.cdc.gov/chronicdisease/about/index.htm.
  2. Woolf SH, Schoomaker H. Life Expectancy and Mortality Rates in the United States, 1959-2017. JAMA. 2019; 322:1996–2016. https://doi.org/10.1001/jama.2019.16932[PubMed]
  3. Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, et al. Geroscience: linking aging to chronic disease. Cell. 2014; 159:709–13. https://doi.org/10.1016/j.cell.2014.10.039[PubMed]
  4. Scott AJ, Ellison M, Sinclair DA. The economic value of targeting aging. Nat Aging. 2021; 1:616–23. https://doi.org/10.1038/s43587-021-00080-0
  5. Bergsma T, Rogaeva E. DNA Methylation Clocks and Their Predictive Capacity for Aging Phenotypes and Healthspan. Neurosci Insights. 2020; 15:2633105520942221. https://doi.org/10.1177/2633105520942221[PubMed]
  6. Belsky DW, Caspi A, Corcoran DL, Sugden K, Poulton R, Arseneault L, Baccarelli A, Chamarti K, Gao X, Hannon E, Harrington HL, Houts R, Kothari M, et al. DunedinPACE, a DNA methylation biomarker of the pace of aging. Elife. 2022; 11:e73420. https://doi.org/10.7554/eLife.73420 [PubMed]
  7. https://fortune.com/well/2023/05/17/how-to-lower-biological-age-lifestyle-changes-diet-exercise-relaxation-probiotics/
  8. https://www.aging-us.com/article/204602/text

Autophagy

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Autophagy is your body’s rejuvenation process that can be turned on by fasting.

Autophagy is our body’s natural recycling process, a system our bodies have used for centuries to survive. It is our body’s way of renewing itself. It involves the breakdown of old, damaged cells and renews them into healthier versions of themselves.

Over time, our cells grow old and become more susceptible to damage, which leads to oxidative stress in the body. This occurs when the body is exposed to harmful substances in the environment called free radicals, which can increase the risk of disease and accelerate aging.

Autophagy’s sole purpose in life is to reverse this negative process as much as possible. It is your friend, and is a protective mechanism to preserve the health of your cells and your entire body.

During autophagy, cells identified as being damaged are broken down, destroyed, and parts of them are reused to generate healthy, more high-functioning cells.

This process needs to occur frequently and long enough to achieve its intended benefits. Fortunately, there are ways to induce autophagy more regularly to support healthy aging and longevity.[1] One of the best ways is through fasting.

Autophagy Fasting Benefits

There are multiple autophagy benefits to health, and fasting is one way to help you achieve these benefits more often.[2] This is the case with both intermittent fasting and prolonged fasting methods.

Denying your cells of nutrients when fasting gives your body (and liver) a break from digestion and allows it to focus on cell renewal.

It then begins to locate the damaged cells that need to go, recreating them to become stronger.

Here are a few possible autophagy benefits associated with fasting:[4]

  • Decreases oxidative stress that leads to early aging.
  • Destroys damaged cells that can cause disease.
  • Bolsters the removal of toxins from the body.
  • Improves hormonal balance.
  • Decreases inflammation.
  • Boosts skin health by increasing collagen production.
  • Supports proper nerve communication and function, helping your body work more efficiently.
  • Promotes the conversion of your food and nutrients into needed energy.

When it comes to your own autophagy fasting timeline and method, it’s important to know yourself and weigh out the pros and cons of starting an autophagy diet plan like fasting.

How to Induce Autophagy By Fasting

Here are a few tips and best practices if you want to start fasting to stimulate autophagy.

Fast for at least 24 hours – While the exact fasting schedule to stimulate autophagy is not yet set in stone, your body needs some time to prepare for autophagy. While some experts say it’s possible to induce autophagy after fasting for 14–18 hours, most research points to at least 24 hours to begin to see a notifiable autophagy effect. For this reason, at least a 24-hour fast with is generally recommended to stimulate autophagy.[5]

Consider extended fasting – It’s possible that more extended fasts of at least 24–48 hours may lead to even bigger autophagic activity. However, this is not easy or necessarily safe for many people to follow.[6] Extended fasting can be especially dangerous for those who take insulin or other medications to manage blood sugar, as this can result in hypoglycemia (low blood sugar).

Add certain foods to speed up the process – There are a few foods you can try to help support the autophagy process during your eating windows. This includes coffee, green tea, turmeric, and polyphenols called ellagitannins and ellagic acid that promote health.[7] These polyphenols break down into Urolithin A

There are other effective (and safe!) ways to induce autophagy that don’t involve drastically changing your diet or eating schedule.

Calorie Restriction

A continuous calorie restriction can provide the same autophagy fasting benefits by “starving” your cells of calories on a more regular basis. You don’t need to go super low on calories to achieve autophagy – just reducing by 10-40% of your maintenance calorie needs can be effective.[8]

To achieve this safely and effectively through this method, it’s best to work with a registered dietitian for guidance.

Exercise

If you need a little extra push to exercise more, let the healthy-aging benefits of autophagy get you going on those unmotivated days. Physical activity has been shown to induce autophagy in muscles, especially after higher intensity exercise like interval training or running.[9]

However, even more prolonged, moderate-intensity exercise like walking produces these same autophagy benefits – you may just have to do it for longer.

Autophagy is your body’s way of self-preserving to delay the aging process, optimize health, and protect you from disease. You hold the tools to induce it more often through your daily habits like fasting, calorie restriction, and exercise.

References:

  1. Nakamura S, Yoshimori T. Autophagy and Longevity. Mol Cells. 2018 Jan 31;41(1):65-72. doi: 10.14348/molcells.2018.2333. Epub 2018 Jan 23. PMID: 29370695; PMCID: PMC5792715.
  2. https://www.timelinenutrition.com/blog/autophagy-and-fasting-unleash-the-power-for-optimal-health

13 Habits Linked to a Long Life

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13 Habits Linked to a Long Life (Backed by Science) from Healthline.com

Eating a nutritious diet and exercising regularly may increase your life expectancy. Other factors, like overeating and drinking more than a moderate level of alcohol, may reduce your risk of certain diseases.