Be Healthier and Live Longer by Eating Less

Researchers at the Longevity Institute of the Leonard Davis School of Gerontology at the University of Southern California have been able to predict the significant risk reduction and life-extending power of periodically mimicking a fasting diet.

According to their study, published in the scientific journal Nature, the potential health benefits gained from moderate, intermittent near-fasting are quite impressive. By periodically following a fast-mimicking diet, they say, it’s possible to delay the biological or physical aging process and have an extended disease-free period of life.

The fast-mimicking diet is a five-day (per month), plant-based diet low in calories and protein, followed by a normal diet supporting new or more functional cell growth. The fast-mimicking diet for study participants included vegetable-based soups, energy bars and drinks, chip snacks, tea, and a high-level vitamin, mineral, and essential fatty acid supplement.

Study participants included 100 men and women ages 18 to 70 and excluded anyone with major physical health conditions or mental illness.

The researchers found that just three monthly cycles of the fast-mimicking diet reduced biological aging by an average of two and a half years. Study participants also experienced weight loss, total body fat loss, reduced abdominal and liver fat, lower blood pressure, reduced triglycerides and cholesterol, lower fasting glucose levels, and reduced insulin resistance, especially in those with higher rates of these risk factors at the beginning of the study.

While ongoing calorie restriction alone can help reduce weight and control disease risk factors, it’s well-documented how difficult it is for most people to maintain a low- to very low-calorie diet for any significant time. For many, a periodic fast-mimicking plan may provide the same, if not more, risk-reducing benefits while less burdening the individual.


References:

  1. https://www.psychologytoday.com/intl/blog/cravings/202403/be-healthier-and-live-longer-by-occasionally-eating-less

Berberine

Berberine is a bioactive compound found naturally in several plants, including a group of shrubs called Berberis. It has a long history of use in traditional Chinese medicine and offers impressive benefits for various health concerns.

Here’s how berberine works and some of its potential health benefits:

Blood Sugar Regulation:

  • Berberine has been shown to significantly lower blood sugar levels in people with type 2 diabetes.
  • It works by:Decreasing insulin resistance, making insulin more effective.
    Increasing glycolysis (breaking down sugars inside cells).
  • Reducing sugar production in the liver.
  • Slowing carbohydrate breakdown in the gut.
  • Increasing beneficial gut bacteria.
  • In a study, taking 1 gram of berberine per day lowered fasting blood sugar by 20%and improved long-term blood sugar regulation.

Weight Loss:

Berberine may aid weight loss by affecting metabolism and energy levels.

It activates an enzyme called AMP-activated protein kinase (AMPK), which plays a key role in regulating metabolism.

Additionally, berberine influences other molecules inside cells and may impact gene expression, potentially protecting against chronic health conditions.

Heart Health:

Berberine has been associated with improved levels of blood lipids (cholesterol and triglycerides).
It may be as effective as certain oral diabetes drugs in managing blood sugar.

Other Potential Benefits:

Berberine might aid in the treatment of conditions such as depression and nonalcoholic fatty liver disease (NAFLD).

Research suggests it could have benefits for cancer, inflammation, and more.

In summary, berberine is a powerful supplement with a wide range of potential health benefits. However, as with any supplement, it’s essential to consult with a healthcare professional before using it.

Chronic Diseases Greatest Threat to Life Expectancy

Chronic diseases are the greatest threat to life expectancy and public health, killing far more Americans between 35 and 64 every year.  ~ Washington Post

While opioids and gun violence in the U.S. have rightly seized the media and public’s attention, heart disease and cancer remained, even at the height of the COVID-19 pandemic, the leading causes of death for people 35 to 64, according to a Washington Post analysis of mortality data.

And many other conditions  have become more common, including diabetes and liver disease. These chronic ailments are the primary reason American life expectancy has been poor compared with other Westen nations.

The pandemic amplified a racial gap in life expectancy that had been narrowing in recent decades. In 2021, life expectancy for Native Americans was 65 years; for Black Americans, 71; for White Americans, 76; for Hispanic Americans, 78; and for Asian Americans 84.

Life expectancy is a wide-angle snapshot of average death rates for people in different places or age groups. The life expectancy metric is a reasonably good measure of a nation’s overall health. And America’s is not very good.

In essence, the U.S. healthcare system geared toward disease and illness treatment rather than prevention. Health care is “the only business that doesn’t reward for quality care. All we reward for is volume. Do more, and you’re going to get more money,” Michael Imburgia, a Louisville cardiologist said.

The rate of obesity deaths for adults 35 to 64 doubled from 1979 to 2000, then doubled again from 2000 to 2019. In 2005, a special reportin the New England Journal of Medicine warned that the rise of obesity would eventually halt and reverse historical trends in life expectancy. That warning generated little reaction.

Obesity is one reason progress against heart disease, after accelerating between 1980 and 2000, has slowed, experts say. Obesity is poised to overtake tobacco as the No. 1 preventable cause of cancer, according to Otis Brawley, an oncologist and epidemiologist at Johns Hopkins University.


References:

  1. https://www.washingtonpost.com/health/interactive/2023/american-life-expectancy-dropping/

Nitric Oxide Sources

Nitric oxide is a molecule that is very important to the way the body works, including how the blood flows, how the immune system works, and how the brain works.

Adding nitric oxide to your diet may help your health in a number of ways, such as lowering your blood pressure, improving your blood flow and exercise performance, and reducing inflammation.

Foods that are naturally high in nitric oxide or help the body produce more nitric oxide include:

  • Beets: Beets are a rich source of nitrates, which the body converts into nitric oxide. They also contain antioxidants and other nutrients that can support overall health.
  • Spinach: Spinach is another excellent source of nitrates and contains various other nutrients, including vitamins and minerals.
  • Berries: Many berries, including blueberries, raspberries, and blackberries, contain antioxidants and other compounds that may support nitric oxide production.
  • Pomegranate: Pomegranate is high in antioxidants and has been shown to support nitric oxide production in the body.

MCT Oil

MCT oil is a supplement from coconut and the molecules are smaller than those in most of the fats you eat, absorbed into the bloodstream quickly leading to higher energy level and more.

MCT Oil (Medium Chain Triglycerides) Benefits:

  • Promotes the growth of healthy gut bacteria, which strengthens the intestinal barrier.
  • Anti-Inflammatory
  • This oil can promote fat loss by increasing your metabolism, reducing body fat
  • Powerfully reduces appetite

Adding it to your morning cup of coffee, in your salad dressing, smoothies, and other non-cooked foods (it has a low smoke point, so avoid using MCT oil where heat is involved). Do not cook with it. Drizzle it over proteins and vegetables.

For beginners, start with 1 tsp.(4 grams) and scale up to 1 tbsp. (15 grams) per day.

Bulletproof Coffee

✔️ Brew a cup of high-quality coffee
✔️ Add 1-2 tablespoons of grass-fed butter
✔️ Mix in 1-2 tablespoons of MCT oil
✔️ Blend until frothy and creamy

Benefits:
✔️ Boosts mental clarity and focus
✔️ Sustained energy without the crash
✔️ Helps with weight management
✔️ Enhances cognitive performance

Quality matters! Use top-notch ingredients for maximum nutrients and effects.

Lifestyle Changes to Diet, Sleep, and Exercise—Paired with interventions Like Relaxation Exercises Could Reverse the Aging Process

A group of mature women lowered their biological age by an average of 5 years in just 8 weeks by lifestyle change consisting of exercise, healthy diet and adequate sleep. 

In the United States, dix in ten adults have at least one chronic disease and four in ten adults have two or more [1]. These diseases are a major cause of morbidity and mortality and they put a significant burden on the U.S. healthcare system as well as the society at large [2].

Aging has been identified as a common driver of chronic diseases and an important target for extending Americans’ healthspan [3]. Life expectancy for Americans has increased dramatically, although not all of the years gained are healthy. It has been estimated that if we improve Americans’ collective healthspan by just one year the calculated savings are worth $38 trillion dollars, and if by 10 years those savings jump to $367 trillion dollars [4].

Biological age clocks, based on DNA methylation marks, have become important surrogate markers to assess the effectiveness of interventions at reducing biological age, with the expectation that biological age reductions will compress morbidity and extend mortality [5, 6].

Lifestyle changes to diet, sleep, and exercise—paired with interventions like relaxation exercises and supplements—could reverse the aging process, according to new research.

Six women between the ages of 46 and 65 underwent an eight-week program that included alterations to diet, sleep, and exercise. They were also given relaxation guidance, probiotic and phytonutrient supplements, and nutritional coaching.

Blood tests showed a reduction in biological age of up to 11 years in five of the six women, with the average participant experiencing a 4.6-year decrease, according to the study, published in March in the journal Aging.


References:

  1. About chronic disease. Center for Disease Control. 2022. https://www.cdc.gov/chronicdisease/about/index.htm.
  2. Woolf SH, Schoomaker H. Life Expectancy and Mortality Rates in the United States, 1959-2017. JAMA. 2019; 322:1996–2016. https://doi.org/10.1001/jama.2019.16932[PubMed]
  3. Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, et al. Geroscience: linking aging to chronic disease. Cell. 2014; 159:709–13. https://doi.org/10.1016/j.cell.2014.10.039[PubMed]
  4. Scott AJ, Ellison M, Sinclair DA. The economic value of targeting aging. Nat Aging. 2021; 1:616–23. https://doi.org/10.1038/s43587-021-00080-0
  5. Bergsma T, Rogaeva E. DNA Methylation Clocks and Their Predictive Capacity for Aging Phenotypes and Healthspan. Neurosci Insights. 2020; 15:2633105520942221. https://doi.org/10.1177/2633105520942221[PubMed]
  6. Belsky DW, Caspi A, Corcoran DL, Sugden K, Poulton R, Arseneault L, Baccarelli A, Chamarti K, Gao X, Hannon E, Harrington HL, Houts R, Kothari M, et al. DunedinPACE, a DNA methylation biomarker of the pace of aging. Elife. 2022; 11:e73420. https://doi.org/10.7554/eLife.73420 [PubMed]
  7. https://fortune.com/well/2023/05/17/how-to-lower-biological-age-lifestyle-changes-diet-exercise-relaxation-probiotics/
  8. https://www.aging-us.com/article/204602/text

13 Habits Linked to a Long Life

13 Habits Linked to a Long Life (Backed by Science) from Healthline.com

Eating a nutritious diet and exercising regularly may increase your life expectancy. Other factors, like overeating and drinking more than a moderate level of alcohol, may reduce your risk of certain diseases.

Exercise as Medicine: Just Get Moving!

You can come up with a million reasons for not being physically active.

Roughly 3.2 million people die each year because of physical inactivity, according to WebMD. Regular exercise — aerobics, resistance, stretching and balance — especially among older adults, is critical to good health.

Healthspan is more important than lifespan. On average, people live up to 20% of our lives unhealthy. Institute for Public Health

But it’s important to know that stillness or lack of exercise is bad for your longevity and healthspan.  “Healthspan” can be defined as the period of one’s life that one is healthy, according to the Institute for Public Health. However, being “healthy” means being free from serious disease. A disease is considered to be serious if it is a leading cause of death.

Caring about extending the well period of one’s life should be intuitive – if one is past their healthspan, it means they are chronically sick, often with a degenerating condition. Therefore, most people would agree that staying within their healthspan is desirable.

To extend a person’s healthspan, first healthcare professionals must be able to measure it.  Once they can measure it, then they can improve it.

Unlike the average lifespan, which is now 79.3 years in the US, healthcare professionals don’t have a statistic to mark the end of the average healthspan. To address this, the World Health Organization (WHO) has developed an indicator, HALE – healthy life expectancy.

To improve healthspan, treatments are required, but treatments don’t necessarily mean drugs. First, there are many commonalities around lifestyle that could delay the onset of most, if not all, of the serious diseases. It might seem like common sense, but maintaining a healthy plant-based diet with regular exercise and without smoking and drinking alcohol and nurturing strong social relationships are the surest ways to promote one’s healthspan and limit the onset of most diseases.

Food, Exercise and Social Connections as Medicine to improve Healthspan.


Resistance:

  1. https://www.webmd.com/healthy-aging/ss/slideshow-truth-about-exercise-aging
  2. https://publichealth.wustl.edu/heatlhspan-is-more-important-than-lifespan-so-why-dont-more-people-know-about-it/
  3. http://apps.who.int/gho/data/view.main.HALEXREGv

Four Types Of Exercise Can Improve Your Health And Physical Ability

Research has shown that it’s important for older Americans to get all four types of exercise or physical activity:

  • Endurance (aerobics),
  • Strength and Resistant,
  • Balance, and
  • Flexibility.

Each exercise or physical activity has different benefits for your health and well-being. Additionally, doing one or more kind of exercise can improve your ability to do the others, and variety helps reduce risk of injury and promote healthy aging over the long term.
Endurance exercises for older adults

Four Types of Exercise infographic. Click to open infographic webpage.

Endurance activities or aerobic exercises increase your breathing and heart rates. These activities help keep you healthy, improve your fitness, and help you perform the tasks you need to do every day. Endurance exercises improve the health of your heart, lungs, and circulatory system. They also can delay or prevent many diseases that are common in older adults such as diabetes, colon and breast cancers, heart disease, and others. Physical activities that build endurance include:

  • Brisk walking or jogging
  • Yard work (mowing, raking)
  • Dancing
  • Swimming
  • Biking
  • Climbing stairs or hills
  • Playing tennis or basketball

Increase your endurance or “staying power” to help keep up with your grandchildren during a trip to the park, dance to your favorite songs at a family wedding, and rake the yard and bag up leaves. Build up to at least 150 minutes of activity a week that makes you breathe hard. Try to be active throughout your day to reach this goal and avoid sitting for long periods of time.

Gauging your exercise intensity

When you’re being active, try talking: if you’re breathing hard but can still have a conversation easily, it’s moderate-intensity activity. If you can only say a few words before you have to take a breath, it’s vigorous-intensity activity.


References:

  1. https://www.nia.nih.gov/health/four-types-exercise-can-improve-your-health-and-physical-ability

Health: There are No Limits

“Once you pass the age of fifty, exercise is no longer optional. You have to exercise or get old.” ~ Dr. Henry S. Lodge. M.S., Younger Next Year, pg. 113.

People tend not to exercise because they are tired at the end of the day, But, in reality, people are tired at the end of the day not because they get to much exercise of physical exertion, explains Dr. Henry S. Lodge. M.D., leading NY internist and Columbia Medical School Professor. Instead, people are tired at the end of the day because they do not get enough exercise and as a result, they are not fit.

People are mentally, emotionally and physically drained and exhausted from being sedentary, states Dr. Lodge. Study after steady demonstrates that productivity increases and an individual functions better each day when they are fit. In short, time spent exercising and getting fit is life enhancing and extending.

So, make daily exercise a habit or routine like taking a shower or brushing your teeth. In short, your body craves the body’s chemical reaction resulting from exercise and movement.  So it’s important for you to “Do Something Everyday”.

Start exercising at a level that matches your current level of fitness, Dr. Lodge urges. Start out a level that is hard enough to make you sweat like walking at a brisk pace for twenty to thirty minutes. But, before you get started, check with your medical doctor.

Getting and staying fit is wonderful if you’re healthy, but it’s essential and life saving if you’re not healthy. Your life will improve dramatically once you commit to the habit of regular exercise.

Your long term endurance exercise goal should be to do long and slow aerobic exercise for three hours or more at 60% to 65% of maximum heart rate for three hours without getting exhausted.  You should be able to do something like an all morning bike ride for three hours or more well into your sixties, seventies, eighties and nineties.  You should make a real commitment to do something like that at least once a month

If you can get to the level of three hours or more of endurance exercise and stay there, life will be good, says Chris Crowley, New York Times bestselling co-author of “Younger Next Year”. Crowley recommends that you:

  1. Exercise six days a week for at least 30 minutes for the rest of your life.
  2. Do serious aerobic exercise four days a week for the rest of your life.
  3. Do serious strength training, with weights or body weight, two days a week for the rest of your life.
  4. Eat healthy foods and drink plenty of water. Quit eating crappy food like refined sugar, refined carbs and processed foods.
  5. Maintain close relationships and social connections.
  6. Get adequate sleep and reduce stress.
  7. Have an attitude of gratitude.  Always be grateful.

“Open heart surgery is hugely popular these days, apparently because so many guys prefer it to learning about aerobic exercise and working out.” ~ Chris Crowley, Younger Next Year, pg. 116.

Crowley believes that it’s possible that Americans, as a society, “can be radically healthier, more energetic, more fit, more optimistic and effective by making modest, behavioral changes. Putting off 70% of today’s aging is a simple matter: Move a lot more!…quit eating crap!…connect with others!, he emphasizes.” The combination of sedentary lifestyle  and the crappy food we eat is wrecking Americans lives and ruining the economy. The nation spends “20% of our national income on health care”. Half of the amount spent on healthcare could be saved “because 50% of our bad health is simply the result of the ridiculous way we eat and live.”

Final thoughts…staying deeply connected with and caring about family and friends and others are essential for healthy aging and longevity. Staying in touch… caring… is hugely important.


References:

  1. Chris Crowley and Henry S. Lodge, M.D., Younger Next Year, Workman Publishing, 2nd Edition, New York, December 24, 2019.
  2. https://www.youngernextyear.com/bios/

“Younger Next Year: Live Strong, Fit, Sexy, and Smart―Until You’re 80 and Beyond” – According to authors Chris Crowley and Dr. Henry S. Lodge, M.D., men 50 or older can become functionally younger every year for the next five to ten years, and continue to live like fifty-year-olds until well into their eighties. To enjoy life and be stronger, healthier, and more alert. To stave off 70% of the normal decay associated with aging (weakness, sore joints, apathy), and to eliminate over 50% of all illness and potential injuries.